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|Tier I||Begin the quest with 3 Cankers that have Brainiac mutations. Learn about mutations by hovering a Canker with your inventory open.|
|Tier II||At the end of each stage, each Canker gains a random mutation.|
|Tier III||[3 Charges] Spawn a Canker, then activate your Canker mutations without destroying any Cankers.|
|Unlock I||Unlock by completing a quest on Normal or above with 10 or more Cankers.|
|Unlock II||Unlock II by completing a quest on Normal or above with 20 or more Cankers.|
|Unlock III||Unlock III by completing a quest on Normal or above with 30 or more Cankers.|
All of a Canker's mutation effects trigger when the Canker is clicked. As Mutant you still lose 1 life for clicking Cankers, unless they are Babyfaced.
Cankers can have many mutations at once, and multiple copies of the same mutation.
- v1.60 Added